LATS1-BECLIN1 MEDIATES A NON-CANONICAL CONNECTION BETWEEN THE HIPPO PATHWAY AND AUTOPHAGY




Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production

FIXED BLADE - CLOSEOUT Thioredoxin reductases are frequently overexpressed in various solid tumors as a protective mechanism against heightened oxidative stress.Inhibitors of this system, such as Auranofin, are effective in eradicating cancer cells.However, the clinical significance of thioredoxin reductase 1 (TrxR1) in lung cancer, as well as the

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